This project has been funded by the Italian Ministry of University and Research (MUR) under the PRIN 2022 programme.
The MASTER project aims to develop a smart and biocompatible device based on magnetic-responsive scaffolds designed to promote tendon regeneration.
These 3D-printed porous systems combine thermoplastic polyurethane with bioactive compounds and magnetic particles to stimulate cell activity and healing processes under magnetic field exposure.
The innovation lies in mimicking the complex tendon-to-bone interface both structurally and biomechanically, enabling localized and tunable therapeutic responses.
The project involves the design and development of highly porous 3D scaffolds based on thermoplastic polyurethane. These scaffolds are doped with chondroitin sulfate (CS) and casein phosphopeptides (CPPs), aiming to mimic the structural, biomechanical, and biochemical properties of the tendon-to-bone interface (TBI).
The materials and processing steps are tailored to support cell adhesion, mechanical strength, and biological integration, following a modular and progressive structure across work packages.
Visual representation of the experimental design and magnetic scaffold application in tendon regeneration.
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Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry's
Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry's standard dummy text ever since the 1500s
The project is coordinated by the University of Pavia (UNIPV), in collaboration with three other Italian universities.
UNIPV acts as the lead institution and manages both project implementation and dissemination activities.
